"Super" Me

Cycle number: 11

Cycle day: 15

Meds: Met

Outlook: bluurghghgh

Well, the results are in: cycle cancelled due to "super-ovulation". I suppose it's sweet of them to try to make me feel successful at something -_- The clinic hadn't rung by lunch time so I called and left a reminder message. Then somehow my phone didn't even ring and the next time I looked at it I had a voicemail. Had to wait til I got out of a meeting at 3pm before I could listen to it. The only advice she had was to come back when I start to bleed....yeh thanks for that.

So I rang again and asked for someone to call me back as I had a few questions. The nicest nurse there called and I went through a few things with her:

- The oestradiol number was high, and from that they deduce that I will ovulate but they can't tell when. She said obviously there was a chance I wouldn't, and/or that one or more of the follicles would become a cyst.

- I shouldn't have sex for the foreseeable future due to the risk of a multiples pregnancy, but she admitted she couldn't stop us if that's what we decided to do.

- Even if I don't develop a cyst, chances are I will have to take next cycle off to let the ovary recover before doing any more treatment.

- My response has been unusual to both Clo.mid and Meno.pur and they couldn't have predicted what would happen, even with the intensive monitoring.

- The dose of Meno.pur I was put on was the standard dose that most people would start at, and for the next active cycle they will probably halve it.

- I should wait 2.5-3 weeks and if I haven't bled yet I should go back for a scan and then induce a bleed.

I'm still feeling really frustrated about this cycle and really upset, and after I put down the phone I just cried for about half an hour. If it's this hard to ovulate what chance do I have of actually getting pregnant? I'm starting to feel scared - what if none of the ovulation induction drugs work on me? What if I only ever over- or under-respond? Will I just have to move straight to IVF without passing go?

We are going to carry on trying this cycle. Me reasoning is this: a follicle that grows beyond about 24mm is considered too big to carry a 100% healthy, ripe egg. I have 2 that were at the top end of this range yesterday, so they will be even bigger by the time I finally ovulate (I did a digital ovulation test yesterday which was negative, so I assume I have a few more days before any eggs will appear) which means the chances of either containing a viable egg are small. Even if such an egg was fertilised it would be unlikely to continue beyond a week or so. So that leaves 2 follicles. If they both release and if they are both healthy there is a small chance both could be fertilised. I'm happy to take that risk.

I just can't sit back and do nothing for the best part of 2 months while life and time just tick away. If this cycle amounts to nothing (which I'm assuming it will) it will be July at the earliest before I get pregnant - and that's assuming that I'm incredibly lucky and get pregnant on my first proper successful cycle (which also seems unlikely). I'm completely fed up of waiting, it's all I seem to do. Wait wait wait wait wait. Everyone else gets a chance each and every month to get pregnant; I haven't even had one chance in the 4 years I've been trying. It's like I'm the only one not to complete a 100m race because I can't even find my way out of the changing room, let alone onto the track and down to the finish line. This is the most depressed and negative I have felt for a long, long time and I don't like it.

Angry Chair

Cycle number: 11

Cycle day: 14

Meds: Met

Outlook: Really f%*!ed off

I am beginning to lose faith in the fertility consultants I see, particularly the one I bemoaned in the last post, even though I am lucky enough to go to a hospital which specialises in fertility.

So after last Wednesday's secretive scan, I toddled back on Friday not knowing what to expect. I was thrilled to discover I had 3 follicles maturing on the right side - one at 14mm, one at 14-15mm and one at 15-16mm - and my lining was looking good. She sent me for another oestradiol test (a horrible man who was clearly new to taking blood (or a sadist) and did the whole thing in painfully slow motion so it hurt as much as possible) and told me to halve my Meno.pur dose over the weekend.

So all weekend I was really excited, even though I was having to waste half a pod of drug each night (so pointless) and, yet again, started to think at last this was the cycle that was going to give us a real chance to get pregnant.

I was told to come back in today and so I went. First off, I had to wait nearly half an hour to be seen in a boiling hot waiting room (so hot a trickle of sweat came down to my elbow from my armpit) and then it was a doctor I've never seen before. He was really thorough at the scan, again saying my lining was excellent and then started measuring the follicles. This is where it started to go wrong. The three she saw on Friday have all grown to a mature size (between 20mm-23mm) but there is a fourth that is catching up (17mm) and a fifth which is smaller. He said I have over stimulated and the cycle would have to be cancelled.

I had to fight back tears on the couch (luckily it was dark so he couldn't see). He then was at pains to explain to me why they would not be giving me the trigger. I asked what would happen if I just ovulated on my own and he said "Well you can't have sex". WHAT?!?! "You could end up with quadruplets and you don't want that! Hahah!" He then spent ages working out the precise dimensions of the offending follicles before saying "Yes this can happen with PCO".........again WHAT?!?!

I then went to sit in the waiting room while he went to get the opinion of a nurse. I went in to see her and she said actually they were going to check the "cycle cancellation" decision with another doctor (Ms Helpful from Wed/Fri) but it looked likely it would be cancelled. She then told me to continue with my half dose of Meno.pur tonight and this time I said it out loud "WHAT?!?" She said she didn't want to be the one to make a decision to stop taking it (i.e. that it should be the doctor telling me) but I was like "Surely if I take more tonight, the biggest ones are just going to get bigger, and the ones that are borderline are going to catch up and there will be even more?" and she said "Ok don't take it tonight" - I was in disbelief. 

She then said I would have to go for yet another blood test (my third in less than a week) and based on my scan and the blood test results she would discuss with Ms Helpful tomorrow and give me a call. I then had to fight back tears all the way up to haematology. And - typical - of all the appointments I've had there, this was the one time Bubble couldn't come with me.

So there are several things that concern/down right annoy me:

• If there were too many follicles growing, why didn't Ms Helpful notice on Wednesday and tell me to halve my dose then?
• If there were definitely too many on Friday, why didn't she get me to stop the Meno.pur over the weekend and reassess on Monday?
• Surely my oestradiol numbers are the most reliable source of info - why after 2 blood tests and all these scans was this not picked up earlier?
• If over-stimulation typically happens with PCOS (and particularly after my over-response to Clo.mid) why wasn't I started on the minimum dose possible? They could then have increased it later on if I wasn't responding well enough
• If I ovulate tonight or tomorrow - as seems likely with follicles that big - telling me not to have sex from now isn't a failsafe way of preventing me getting pregnant since we already did it yesterday! So they have put me at risk of conceiving 4 babies
• If my follicles are already so big that I could ovulate at any given time, why then increase the chance of adding a couple more to that number by telling me to continue with the Menopur tonight?! And why did the nurse try to take the decision herself if she wasn't sure (which she obviously wasn't since my layman response made her change her mind)?
• Are these large follicles actually going to rupture at all, or am I going to be left with a mass of uncomfortable cysts that need another cycle off to get rid of?

Overall I'm gutted. It's now been 7 months since we started treatment. This is only my third medicated cycle and the third that has been a wasted opportunity for a pregnancy. All this just to ovulate, and I'm not even getting that right! Pregnancy seems a very very long way away tonight, and a real, actual baby even further. I can't believe that with all the injections, all the blood tests, all the appointments, somehow this has still gone wrong.

Of course, they can't stop us going ahead and having sex if we want to. And a large part of me is very tempted - why should I waste the only chance I've had so far?! Will wait and see what they say tomorrow, but I'm not holding my breath.